In plain view from Centraal Station, the magnificent cupola and neo-Renaissance towers belong to the city's main Catholic church, the first built after Catholic worship became legal again in the 19th century. St Nicholas is the patron saint of seafarers, so the church became an important symbol for Amsterdam.

The interior is notable for its high altar, the theatrical crown of Emperor Maximilian I and depictions of the Stations of the Cross, on which tireless painter Jan Dunselman laboured for 40 years. Worship services take place daily at 12.30pm, except on Sunday (10.30am and 1pm).