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Soil shipped from Calvary during the Crusades is said to lie within the white walls of this hauntingly beautiful, final resting place for many prominent Pisans, arranged around a garden in a cloistered quadrangle. During WWII, Allied artillery destroyed many of the cloisters' frescoes, but a couple were salvaged and are now displayed in the Sala Affreschi (Frescoes Room). Most notable is the Triumph of Death (1336–41), a remarkable illustration of Hell attributed to 14th-century painter Buonamico Buffalmacco.

Fortunately, the mirrors once stuck next to the graphic images of the damned being roasted alive on spits have been removed – originally, viewers would have seen their own faces in the horrific scene. Buffalmacco's Last Judgement & Hell (1333–41), in the same room, is equally brutal.