Prague is a relatively safe city and visitors are not subject to any major health dangers that one wouldn’t find in any other large European city.
The quality of medical care in Prague is high, and rest assured, if you do suffer a medical emergency you will receive proper care. Prague has several large hospitals, with trained staff used to dealing with foreign visitors.
Na Homolce Hospital Widely considered to be the best hospital in Prague, equipped and staffed to Western standards, with staff who speak English, French, German and Spanish.
Polyclinic at Národní A central clinic with staff who speak English, German, French and Russian.
Canadian Medical Care A pricey but professional private clinic with English-speaking doctors.
You'll see plenty of lékárna (pharmacies) throughout the Czech Republic, identified by a big green cross on the outside. In addition to dispensing prescription medications, pharmacies are usually the only places you'll find common over-the-counter drugs like aspirin, cough syrup, cold medications, and the like.
Most pharmacies keep normal business hours, but each district has at least one late-hour dispensary for emergencies. To find the pharmacy in your district, go to any nearby pharmacy; information is usually posted on the door. Lékárna U Sv Ludmily is a neighbourhood pharmacy with a 24-hour window.
There are no vaccinations required for visiting Prague.
Tap water is safe to drink in Prague, though nearly everyone drinks bottled water.