Montrose is an agricultural center and a wholesale supply point for Telluride, 65 miles to the south. With the lofty San Juan Mountains to the south, the Black Canyon of the Gunnison National Park to the east, the Grand Mesa to the north and the Uncompahgre Plateau to the west, it's a handy starting point for adventure. Historic buildings provide the old center with atmosphere, which is distinctly missing on the north–south US 550 route with huge chain stores, motels and fast-food restaurants.
Though rather perfunctory, there are some good museums, antique stores and a clutch of decent restaurants. But perhaps the best reason to stay in Montrose is to day-trip to the awesome Black Canyon of the Gunnison National Park and to pursue mountain biking on the Uncompahgre Plateau.