The most northern of Mexico's fabled silver cities, fascinating Zacatecas – a Unesco World Heritage site – runs along a narrow valley. The large historic center is jam-packed with opulent colonial buildings, a stupendous cathedral (a useful central landmark), magnificent museums and steep, winding streets and alleys. Excellent restaurants and fine hotels make it a very comfortable location for any traveler.
The city has a legacy of historical highs and lows: it was here that Pancho Villa defeated a stronghold of soldiers (today he is still much feted by the locals). Here, too, thousands of indigenous slaves were forced by the Spanish to toil in the mines under terrible conditions. Today, travelers can have their own lofty experiences in a teleférico (cablecar) to the Cerro de la Bufa, an impressive rock outcrop; the trip affords great views of a collage of church domes and rooftops. Alternatively, you can drop below the surface to tour the infamous Edén mine, or vibrate to the rhythms of its underground disco.