Fort Myers

Nestled inland along the Caloosahatchee River, and separated from Fort Myers Beach by several miles of urban sprawl, the city of Fort Myers is often defined by what it's not: it's not an upscale, arty beach town like Sarasota or Naples, and it's not as urbanely sophisticated as Tampa or St Petersburg. While it isn't a city to base a trip around, it's worth a trip to browse its brick-lined main street and visit Thomas Edison's winter home and laboratory.