Nestled inland along the Caloosahatchee River, and separated from Fort Myers Beach by several miles of urban sprawl, the city of Fort Myers is often defined by what it's not: it's not an upscale, arty beach town like Sarasota or Naples, and it's not as urbanely sophisticated as Tampa or St Petersburg. While it isn't a city to base a trip around, it's worth a trip to browse its brick-lined main street and visit Thomas Edison's winter home and laboratory.
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