State-of-the-art NEMO Science Museum (nemosciencemuseum.nl; €21.50) is truly interactive, with four floors of investigative mayhem that kids of all ages will enjoy. Experiment with lifting yourself via a pulley, making bubbles and designing your own wind turbine. Almost everything is labeled in English. You need several hours to see it all.
Italian architect Renzo Piano designed the impossible-to-miss green-copper building, and it's almost surrounded by water. The huge, sloping NEMO Rooftop Viewpoint space, accessed via the museum or stairs in the southeastern corner, has some of the best views over Amsterdam.