Guadalajara’s cathedral is the city’s most beloved and conspicuous landmark with distinctive neo-Gothic towers built after an earthquake toppled the originals in the mid-19th century. Begun in 1558 and consecrated in 1618, the building is almost as old as the city itself. Time your visit right and you’ll see light filter through stained-glass renderings of the Last Supper and hear a working pipe organ rumble sweetly from the rafters.

The interior includes Gothic vaults, massive Tuscan-style gold-leaf pillars and 11 richly decorated altars that were given to Guadalajara by King Fernando VII of Spain (1814–33). The glass case nearest the north entrance is an extremely popular reliquary, containing the hands and blood of the martyred Santa Inocencia. In the sacristy, which an attendant can open for you on request, is La Asunción de la Virgen, painted by Spanish artist Bartolomé Murillo in 1650. Of course, architectural purists may find flaws. Much like the Palacio de Gobierno, the cathedral is a bit of a stylistic hodgepodge, including Churrigueresque, baroque and neoclassical influences.