Ten kilometers south of Manzanillo is the moving sight of the sugar estate of Carlos Manuel de Céspedes, whose outcry, known as 'Grito de Yara', and the subsequent freeing of his slaves on October 10, 1868, marked the opening of Cuba's independence wars. There's a small museum and the Demajagua bell that Céspedes tolled to announce Cuba's (then unofficial) independence.
In 1947 an as-yet-unknown Fidel Castro 'kidnapped' the bell and took it to Havana in a publicity stunt to protest against the corrupt Cuban government.
Also at La Demajagua are the remains of Céspedes' original ingenio (sugar mill) and a poignant monument (with a quote from Castro). To get here, travel south 10km from the Servi-Cupet gas station in Manzanillo, in the direction of Media Luna, and then another 2.5km off the main road, towards the sea.