Built in 1510 by Charles V, this is the first convent of the Dominican order founded in the Americas. It also is where Father Bartolomé de las Casas – the famous chronicler of Spanish atrocities committed against indigenous peoples – did most of his writing. The vault of the chapel, remarkable for its stone zodiac wheel carved with mythological and astrological representations, is worth a look. On the walls are various paintings of religious figures, including Pope Saint Pius V.