Midtown is big, bold and best seen on foot, so slice it up and enjoy it bit by bit. The top end of Fifth Ave (around the 50s) makes for a fabled introduction. It's here that you'll find glam icons like Tiffany & Co and the Plaza Hotel, not to mention the incredible Museum of Modern Art (MoMA). You could easily spend an entire day at the latter, ogling masterpieces, eating, drinking, catching a film and shopping for books and design objects. Unlike most major museums, it's open on Monday. From here, it's only a few blocks south to the Rockefeller Center and its sky-high Top of the Rock observation decks, best visited as the sun sets over the city. A day in Midtown East could easily incorporate rare manuscripts at the Pierpont Morgan Library, beaux arts architecture at Grand Central Terminal, the art deco lobby of the Chrysler Building and an afternoon tour of the United Nations. If it's a rainy day, lose yourself in the gilded New York Public Library. Across in Midtown West, design and fashion buffs shouldn't miss the Museum of Arts & Design and the Museum at FIT. Between the two is bright, blinding Times Square, most spectacular at night. It's here that you'll find a TKTS Booth selling cut-price Broadway tickets. The queues are usually shortest after 5.30pm, but if you're really clever, you'll have bought your tickets at the less crowded South Street Seaport branch. The real gems of Times Square, however, are on its periphery, among them sheet-music specialist Colony, cocktail den the Rum House and dive bar Jimmy's Corner. Further west is Hell's Kitchen, best known for its kicking restaurants, bars and gay scene.