Río Hondo (Deep River), 50km east of El Rancho junction and 130km from Guatemala City, is a transit point, there's very little in the way of sights and attractions. The junction is where Hwy 10 to Chiquimula heads south off the Carretera al Atlántico (Hwy 9). Beyond Chiquimula are turnoffs to Copán, just across the Honduras border; to Esquipulas and on to Nueva Ocotepeque (Honduras); and the remote border crossing between Guatemala and El Salvador at Anguiatú, 12km north of Metapán (El Salvador).
The actual town of Río Hondo is northeast of the junction. Places to stay hereabouts may list their address as Río Hondo, Santa Cruz Río Hondo or Santa Cruz Teculután. Nine kilometers west of the junction are several attractive motels right on Hwy 9. By car, it's an hour from here to Quiriguá, half an hour to Chiquimula and 1½ hours to Esquipulas.