Most travellers who pass through the Chiquimulilla are likely to be surfers heading to or returning from La Libertad in El Salvador. Most people shoot straight through Escuintla and Taxisco to Chiquimulilla and on to the Salvadoran border at Ciudad Pedro de Alvarado–La Hachadura, from where it is about 110km along the coast of El Salvador to La Libertad.
If you need to stop for the night before crossing the border, you could do worse than the low-slung cowboy town of Chiquimulilla in the ranching country some 12km east of Taxisco. There isn't much going on here, but it's a decent enough place to take care of errands and regroup. The bus terminal is on the outskirts of town, but tuk-tuks will take you anywhere you want to go for Q5.