Getting there & away
From Panama City, a regular bus service to Colón (US$2.50, two hours, every 30 minutes) departs from the Albrook Bus Terminal.
Colón’s Terminal de Buses is at the intersection of Calle Terminal and Av Bolívar. It serves towns throughout Colón Province, including:
Escobal (US$1; 1hr; hourly)
La Guayra (US$2.50; 1½hr; hourly) In La Guayra, you can catch the boat to Isla Grande.
Nombre de Dios (US$3; 1½hr; hourly)
Portobelo (US$1.50; 1hr; hourly)
The same buses can be boarded at Sabanitas, the turnoff for Portobelo, thus avoiding a trip into Colón.