Prune

American in East Village & Lower East Side

Expect lines around the block on the weekend, when the hungover show up to cure their ills with Prune's brunches and excellent Bloody Marys (in a dozen varieties). The small room is always busy as diners pour in for grilled trout with mint-and-almond salsa, seared duck breast and rich sweetbreads. Reservations available for dinner and lunch only.