Famous for growing Colorado's best peaches, this small town owes its luck to a warm, dry microclimate that later turned out to also be ideal for vineyards. Bordeaux-style grapes do well here, though you will find a bit of everything on offer. Relatively new on the scene, Palisade vineyards cannot compare to those in Napa Valley, but they do offer a fun outing into this blue-sky farmland. Palisade also offers good mountain biking that's not yet widely known with the newly developed Palisade Rim Trail.
Utes were the first inhabitants of the Grand Valley, followed by white settlers around 1881. It didn't become a popular area for agriculture until the Bureau of Reclamation built irrigation canals to divert water from the Colorado River in the early 1900s. Today it's a pleasant small town with a farm feel and entrepreneurs focused on developing the accoutrements of a wine-country culture.