Fly into Entebbe and get your first taste of wildlife at the Uganda Wildlife Education Centre (UWEC) and the Ngamba Island Chimpanzee Sanctuary – both home to injured or orphaned animals rescued from around Africa. Spend the next day sightseeing in Kampala, dining at one of its cosmopolitan restaurants, before a boozy night on the town. Cure your hangover the next day by being flung into the Nile while white-water rafting in Jinja, 80km east of Kampala. Then it's time to head west for some serious wildlife watching. Begin with the unforgettable experience of gorilla tracking in Bwindi Impenetrable National Park. Then it's further north to Queen Elizabeth National Park for tree-climbing lions, hippos and elephants to finish your one-week visit.
A more generous time frame, which allows you to take in the activities of the 10-day itinerary plus you can chill out on scenic Lake Bunyonyi, and head to Murchison Falls National Park for more animals and thundering waterfalls. Finish up by ticking off the Big Five at Ziwa Rhino Sanctuary on the way back to Kampala.