I came across this word today and have never heard it before. A search on Google suggests it may mean something along the lines of 'irritating', but I can't find a definition for it. The search had just 171 hits, but a handful were on (UK) news websites. Examples:
"What's the most vexing aspect of having young children? I could now wander away for an hour or so and let all the parents fill the page themselves. For me, however, the most irradiatingly nigglesome change has been walking very slowly." timesonline.co.uk
"Granted, it was an easy mistake - despite 15 American hits, Tommy James never once troubled the British charts, so Tiffany's is the only version most people here would know. Nonetheless, it's nigglesome. To have a favourite song of mine attributed to someone who sang it only because it was an easy route to a number one record defiles it." guardian.co.uk
"Poor puss has a terrible itch. She'll go to any lengths to extract her unwanted guest. After hoovering, washing, haircuts and brushing, it seems a lost cause. But our feline heroine has a few tricks up her sleeve and with her jungle cousin's help she soon sends her nigglesome nit packing." from a book description
So does anyone know just what this word means?

