Keep in mind the US is severely lacking a Hostel Network and good modern public transport, compared to EU or Asia...its is a automobile culture, and lodging is cheap hotels/motels, then on up to National Chains and so forth. AirBNB is a very good option in expensive areas like Chicago, San Fra nnd most of California coastal areas, as well popular vacation destinations in mountains and beaches areas...hotels can be $$$ or few choices.
Southwest Airlines is a popular and well run modern airline, with no fees for changes, other than the new fare difference, and you can cancel use the funds for other flights no problem for up to 1 year. You cand take a carry on, and check two bags, for free. They fly to most major cities.
Cities with very good public transport options
NYC
Boston
San Fran
Chicago
Philly
Wash DC
Cities with good public transport options-
Minneapolis
LA
Atlanta
Denver
Adventure Travel to Colombia, Costa Rica, Nicaragua, Honduras, Guatemala, Mexico, Thailand, Burma, Laos, Cambodia, Vietnam, China, South Africa, Morocco, Turkey, EU, USA National Parks, enjoying culture, cuisine, motorcycling, scuba diving, surfing, sailing, rafting, hiking, fishing, camping, nature, wildlife. Get a Guidebook, and get lost!