We are planning a two-week trip in September: to Switzerland (1 week) and Italy (1-week)
- Would like to start from Zurich and end in Italy. Plan to hire a car to see country-side in Switzerland and hop-on to Bernina Express (various reviews recommend Bernina Express instead of Glacier Express)
- About Italy - do not know where to start and end but would like to see Venice, Rome, Vatican, Florence and city of Pisa
Grateful is someone suggests perfect itinerary

jvr333
1

clementis_fur_cap
One week is far too little time for a "perfect" itinerary for those Italian destinations.
Or even a highly imperfect one.
I'd suggest picking 2 (the Vatican is basically a part of Rome).
Pro tip