I completely understand the fear of losing your professional tools. I'm freelance, so my entire working life is in one laptop.
I use Dropbox to back up everything on my hard-drive, and make sure my insurance (either travel insurance or local contents insurance) covers all my important stuff. So far, it's been a complete waste of money as hostels will either have lockable storage (key-cards for doors, with the codes changed for every guest, and your own padlock for any lockers).
I'm a huge fan of hostels when arriving in a new city. It is honestly one of the best sources of up-to-the-minute free information on everything: Work, vacancies, renting, sightseeing, cheap eats, et al. This especially applies to Amsterdam, which is hugely popular for 'buitenlanders' (foreigners) here on working visas.
If you're not comfortable (and I also understand being slightly apprehensive if you've not stayed in hostels before), please at least consider spending a few nights in a hostel here and there. You'll make a couple of friends, put your toe in the water with the hostel experience, and find the cheapest beer :-)