With a new TGV line, what are some stops of interest in France & Germany. I'm sure there are lots of vineyards, what else?
LGV Est
The TGVs serve the route
- Munich (no wine, but worldfamous for its beer)
- Stuttgart (may gain the price for the closest vineyards to the main railway station)
- Karlsruhe (wine region Baden, but no vineyards directly in Karlsruhe)
- Strasbourg (wine region Alsace, but no vineyards directly in Strasbourg)
- Paris Est
The ICEs serve the route
- Frankfurt (no wine, better known for it's apple wine. But some wine regions nearby (e.g. the Rheingau).
- Mannheim (no vineyards there, but in the mid of 4 wine regions: Rheinhessen, Pfalz, Baden, Hessische Bergstrasse)
- Kaiserslautern (forests)
- Saarbrücken (not sure, close to the Mosel-Saar-Ruwer wine region)
- Forbach
- Metz (not sure)
- Gare de Lorraine TGV (a station in the middle of nowhere)
- Paris Est
There are also trains using this highspeed route (at least partly) to Luxembourg and to Switzerland.
German wine regions (map)
Stuttgart: Mercedes-Benz Museum, other museums, spas; nearby Esslingen and Ludwigsburg
Karlsruhe; gateway to
Baden-Baden and the Black Forest (Strasbourg would do as well as gateway for these places)
- Mannheim not that interesting, but perfect gateway to nearby
Heidelberg and Speyer
- Kaiserslautern
- Saarbrücken; nearby
Völklinger Hütte (ironworks - UNESCO world herigate site)

The TGV in France runs through several wine regions, Champagne, Burgundy, Alsace, Strasbourg is a lovely town on the French side and Mainz is often overlooked for a trip up the Middle Rhine where they keep the castles. And there's always cathedrals.
Here are some stories where wine and the TGV / ICE meet.
Route Grand Crus
Dijon near TGV
Wine Road Alsace
Strasbourg
German Wine Road
Mainz