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10

No problems, did it in reverse, but as guyfromrio says wrap up warm (I had thermal, jumper and fleece on and was freezing!)

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11

No problem at all.

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12

I took the night bus on this route about 8 months ago and it took much longer than the corressponding bus during the day. An extra 9 hours altogether because of a break down and the change in route. I think they take a different route at night but maybe someone else has more up to date info.

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13

was about 11 hours from cartagena to medellin by night I think (got caught up in traffic going into medellin)

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14

hi...
I hope you have a good trip ...
the bus from medellin to cartagena is very safe ...the road is long but you can know different and beautiful places.
good luck!

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