Germuno answered this question with some great info, why are you asking again?
[http://www.lonelyplanet.com/thorntree/thread.jspa?threadID=1549624&tstart=50]
His REPLY-
both curitiba & panama city have the same population...but the similarity mostly ends there...
curitiba is cleaner, safer, more expensive, different language.
.. panama city is sea level on the pacific & closer to the atlantic than curitiba which is in the mountains
...both have train access to the atlantic...2 hours to colon from panama city
... twice as long a train ride to paranagua from curitiba & twice as enjoyable...one of the greatest short train rides in the world
..if you got the extra $$$ & portuguese is no problem & you don't need the ocean at your doorstep...it's panama city