Hola, I have to catch a flight around 6:30 am out of Guatemala City. Would appreciate any hotel or other recommendations that will simplify the early morning departure.

I've been satisfied with Villa Toscana the last few summers. http://www.hostalvillatoscana.com/index_ing.php
Another one which is right next to the airport and gets good reviews:
Don't feel like you have to be tied into that area though. It's just as easy to stay in Zona 10 (Holiday Inn, Westin, etc.) and get a cab from there, really just a difference of a few minutes.
Villa Toscana gets my vote, too - when I have an early flight it's awesome being literally 2 minutes from the airport (more sleep :-).
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