A small ferry runs throughout the day from Mtwara's dhow port and fish market over to Msangamkuu Peninsula, taking about 15 minutes for the crossing (Tsh300).
Minivans for the border post of Kilambo depart Mtwara daily between 6am and 8am from in front of Chilindima Guesthouse, one block southwest of the bus stand.
Air Tanzania flies three times weekly between Mtwara and Dar es Salaam. The office is around the corner of the Bodi ya Korosho building.
Five to six flights weekly connecting Mtwara and Dar es Salaam. It's located at the post office.
Mtwara Airport handles domestic and regional flights.
Mtwara's main bus stand is near the market.