Many bus offices are in the center, though most southbound trips originate in Tumbes. Combis leave for Tumbes (S12, two hours) regularly; they drive along the main drag until full. Bus-camas from Máncora go direct to Lima (14 hours); other services can drop you in intermediate cities on the way to Lima (18 hours). Regular minibuses run between Máncora and Punta Sal (S5 to S7, 30 minutes).
Cifa Cheap daily buses to Guayaquil (S65) and Cuenca (S65) in Ecuador.
Civa Has an economical 3:30pm service to Lima, as well as nicer buses at 5:30pm and 6:30pm. Also has a midnight bus to Guayaquil.
Cruz del Sur Has bus-cama services to Lima at 5pm and 5:30pm; buses to Trujillo and Chimbote on Tuesday, Wednesday, Friday and Saturday at 10:30pm; and you can catch its Guayaquil-bound bus from Lima at 9am on Monday, Tuesday, Thursday and Saturday.
El Dorado Six buses a day to Piura between 9:30am and 9:30pm, as well as buses for Chiclayo (9:30am, 9:30pm, 11:30pm and midnight) and Trujillo (9:30am, 9:30pm and 11pm). A Tumbes-bound bus also grabs passengers seven times a day.
Emtrafesa Heads to Chiclayo at 9:30pm and 10pm, and Trujillo at 8:30pm, 9:30pm and 10pm.
Eppo Fast and regular hourly buses to Sullana and Piura between 4am and 8pm. They will also drop you at Los Organos for S2.
Ittsa Direct buses to Lima at 4:15pm and 9:15pm. Other services include Trujillo at 9:15pm, Chimbote at 4:15pm and Chiclayo at 9:15pm.
Oltursa Lima bus-cama (with wi-fi) at 5pm and 5:30pm. Has a direct bus to Trujillo at 10pm.
Sertur Fast colectivo vans to Piura (departing hourly from 8am to 8pm) and Tumbes (departing hourly from 8am to 6pm).
Tepsa Lima bus at 6pm.
Transportes Chiclayo Direct services to Chiclayo at noon, 4:30pm, 10pm and 11pm in comfortable buses.
Transportes Flores One of the more economical buses running to Lima, with departures at 10am, 1pm, 5pm and 7pm.