There are no shortage of hiking and camping opportunities available for intrepid travelers. Be aware that the Naso community has a more established presence in Wekso (Bocas del Toro Province), so you're better off approaching the park from the Caribbean side if you’re interested in spending time with this indigenous group.
There are three short trails that offer fine views of the mountains, the highest in Panama. At the time of research they were closed due to flood damage but may reopen soon.
Most of the park is inaccessible terrain high up in the Talamanca mountains. It's worth making the trek, though, as the park is home to a recorded 90 mammal species and all six cat species. More than 450 bird species have also been recorded here, including quetzals and harpy eagles.