This anthropology and natural history museum, housed in a lovely colonial building, contains many well-preserved pieces of pottery dating from 5000 BC until the Spanish conquest, some of which were found at excavation sites outside Parita. There are also replicas of huacas (golden objects placed with indigenous peoples at the time of burial) found on the peninsula, as well as a recreated chieftain's tomb.

On the 2nd floor you’ll find some excellent folkloric costumes, including an ornate pollera (Panama's national dress) and devil masks. The collection includes many religious artifacts too, including the original bell of Chitré’s cathedral, which was cast in 1767. Signs are in Spanish only.