Zapotrek specializes in hiking, biking and driving trips among indigenous Zapotec villages and their often-spectacular countryside with the help of local guides and experts, opening windows on Zapotec culture and eating local meals, often in local homes. It's run by English-fluent Eric Ramírez, a native of Tlacolula, 31km east of Oaxaca.

Options include hiking up a sacred mountain near San Bartolomé Quialana, visiting mezcal plantations and distilleries east of Ocotlán, and a unique approach to Hierve el Agua. Day-trips cost US$110 to US$150 per person (minimum two people).