Sekong sits on a big westward bend in the Se Kong river, which means that, counter-intuitively, you enter the city from the northeast if driving in on Rte 16 from the west.

The town essentially follows three roads running parallel to the river with the city centre at the top and the ferry landing at the bottom. Most facilities of interest to travellers, including the market and many hotels and restaurants, are on the road closest to the river.