If you want to experience Pakse's mild nightclub scene, head east of the city on Th 38 to a handful of spots that stay open to 1am. Otherwise, stick to the bars in the tourist centre and along Th11.
Spots for a Sundowner
Le Panorama is a required stop for a sunset Beerlao or two. For a more local touch, there are a few floating restaurants, including Banlao, along the rivers that catch some of the twilight. For the best sunset, cross the Souphanouvong Bridge and walk left to the mouth of the Se Don River, or continue to one of the bars on the Mekong River just past it.