The first thing you'll see as you step off the boat is the Ex-Stabilimento Florio della Tonnara, Favignana's historic tuna factory. Vincenzo Florio Sr (1799–1886), a brilliant Palermitan businessman who had made his name in the sulphur, shipping and Marsala industries, also invented a way of steam-cooking and preserving canned tuna that revolutionised the fish-packing industry and cemented the success of his family's business empire. This tonnara, one of many the Florios ran around Sicily, operated until 1977; since 2010 it has operated as a museum.

Favignana town's other significant building, Palazzo Florio, was built in 1876 for Vincenzo's son Ignazio, who purchased the Egadis in 1874. It now houses the tourist office, among other things.

The best beaches are on the southern side of the island at Miramare and Lido Burrone. The latter is a dreamy place for a swim, with a long, graceful stretch of sand lapped by clear aquamarine waters and backed by nice views of Monte Santa Caterina. On the north side, the bays at Cala Rossa and Scalo Cavallo are also lovely swimming spots.