Check out Lonely Planet's Accessible Travel Project for more information: www.lonelyplanet.com/travel-tips-and-articles/travel-for-all-join-lonely-planets-accessible-travel-project. Download the related document for helpful resources: media.lonelyplanet.com/shop/media/accessible-travel-online-resources.pdf. Also download Lonely Planet's free Accessible Travel guides from http://lptravel.to/AccessibleTravel.
Only high-end hotels in Bissau are likely to have lifts or other amenities designed for travellers with disabilities. Streets and footpaths are potholed or uneven and ramps scarce. Accommodation at some budget hotels is on the ground floor; however, bathroom access can be difficult. Challenges like these are only partly offset by the fact that Bissau-Guineans are usually very accommodating and helpful.
As for local transport, none are wheelchair equipped. Pricey 4WD vehicles are available for rent in Bissau.