Numerous boats in the harbour offer day trips to nearby beaches and islets.
Try scuba diving with Samos Dive Center. Professional instructors lead dives in search of moray eels, sea stars, octopuses, lobsters and other critters lurking in the sponge-covered crevices around Pythagorio. A two-dive half-day for beginners costs around €50; a full-day dive, including open-water options, starts at around €85. Snorkelling (€20) is also offered.