Cycle lanes thread all through Kos Town, with the busiest route running along the waterfront to connect the town with Lambi to the north and Psalidi to the south. Many hotels have bikes for guests, or you can rent one from Escape Rentals or Kos Mountainbike Activities.
Local buses, run by KEAS, operate within Kos Town, the most useful being route 3 to Asklepieion; the bus stop is on Akti Miaouli.
Buses to the rest of the island, including the airport, depart from the KTEL bus station. Note that Kefalos-bound buses also stop at the big roundabout near the airport entrance.