Kardamyli is on the main Areopoli–Kalamata road. The central square, Plateia 25 Martiou 1821, lies at the northern end of the main thoroughfare.

Kardamyli’s main pebble-and-stone beach is off the road to Kalamata; turn left beyond the bridge on the northern edge of town. The road to Old (or Upper) Kardamyli is at the bridge.