From Carlisle's tiny airport, 8 miles northeast of the city centre, Loganair (www.loganair.co.uk) operates direct flights to/from London Southend, Dublin and Belfast.
National Express coaches depart from the bus station on Lonsdale St for destinations including London (£25.50 to £39.10, 7½ hours, two or three direct daily), Manchester (£17 to £24.40, three to 3½ hours, three daily) and Glasgow (£12 to £17.10, two hours, four to six daily).
Bus 554 goes to Keswick (£14.60, 70 minutes, four daily Monday to Saturday, three on Sunday) and bus 104 goes to Penrith (£6.30, 40 minutes, half-hourly Monday to Saturday, nine on Sunday).
Carlisle is on the west-coast line from London to Glasgow. It's also the terminus for the scenic Cumbrian Coast and Tyne Valley lines, as well as the historic Settle to Carlisle Railway across the Yorkshire Dales. The following are the main destinations:
Glasgow £28.50, 1¼ hours
Lancaster £32.40, 45 minutes
London Euston £119.70, 3½ hours
Manchester £56, two hours 10 minutes
Newcastle-upon-Tyne £16.70, 1½ hours