Cairo is not well-equipped for travellers with mobility issues. Street curbs are high, entrances to most public buildings and historic sites aren't fitted out with ramps or other accessibility measures and rooms with full accessibility features are only found in top-end hotels. In saying that, intrepid travellers with disabilities shouldn't completely write Cairo off. In general you'll find locals willing to help with any difficulties and hiring taxis for the day is very affordable, making getting around easier.
Egypt For All This travel company specialises in making tailor-made travel arrangements for wheelchair users and travellers with other mobility issues, from day trips to complete Egypt packages.