Most Yasuní lodges use the Puerto La Misión dock within Hostería La Misión. You will be told about your departure point well in advance if on a guided tour.
Coop de Transportes Fluviales Orellana offers a passenger service downriver to Nuevo Rocafuerte, on the Peruvian border (and back upriver again). It departs Monday, Wednesday and Thursday at 7am for Nuevo Rocafuerte ($18.75, 8 to 10 hours). It returns to Coca, departing Nuevo Rocafuerte on Wednesday, Saturday and Sunday at 5am (12 to 14 hours).
Although there’s usually a stop for lunch, bring food and water for the long trip – and be ready at Coca's main dock 30 minutes before departure. On the days the above service does not run, there is normally another boat doing the journey instead, with departures at around 7am. Ask at the dock about faster boats, which big groups can charter to the border.
Coca, among its growing number of boasts, has one of Ecuador's best new bus terminals; the bus station is 3km north of town. A taxi here costs around $2 to $2.50. All main destinations are served.
Rancheras (open-sided buses, or trucks mounted with uncomfortably narrow bench seats, also known as chivas) leave from the market on Alejandro Labaka two blocks back from the river, heading for various destinations between Coca and Lago Agrio, and to Río Tiputini to the south. Cooperativa Camionetas Río Napo pickup trucks and taxis provide services around/outside town.
Buses run to Tena ($8.75, four hours), where you can change for Oriente destinations further to the south; Lago Agrio ($3.75, two hours); and Quito ($11 to $12, six hours via Jondachi or 10 hours via Lago Agrio).