Buses run regularly to/from Brno (75Kč, 1¼ hours) and several times daily direct to Prague (165Kč, three hours). The main bus station is located about 500m west of the centre.
Car & Motorcycle
Třebíč is an easy two-hour drive from Prague, down the D1 motorway in the direction of Brno, turning south at Velké Meziříčí and following the signs. From Brno, the one-hour drive heads northwest on the D1 toward Prague, turning south at Velké Meziříčí. From Telč it's a straight shot (40 minutes) east along local Hwy 23.
From Brno, trains leave every hour or so for Třebíč (92Kč, 1¼ hours). Train travel is not recommended from Prague, with most connections requiring at least two changes. The train station is located about 1km south of the centre.