The bus is generally the best way to access Mikulov from Brno (75Kč, 1½ hours), with coaches leaving hourly. Regional bus service is also good, with frequent buses to both Valtice and Lednice (20Kč, 30 minutes). Buses depart from a tiny station near the train station or at another stop, closer to the centre, called U parku.
Car & Motorcycle
Mikulov, situated between Prague and Vienna, is a three-hour drive from Prague. From Brno, the drive takes around an hour, along highway E461.
Mikulov is poorly served by train and lacks direct lines to major cities, though there are a few handy connections. Several daily trains run to both Valtice (20Kč, 15 minutes) and Znojmo (70Kč, 50 minutes). Trains running in the Valtice direction normally terminate at busy Břeclav junction, which has onward connections to Prague, Brno and Vienna.
The tiny train station is a 20- to 30-minute walk southwest of the centre. See the timetable online.