Services from Prague's Zličín bus station (200Kč, four hours, up to five per day) require changes at Plzeň and Tachov.
Car & Motorcycle
The drive from Prague,173km west of Mariánské Lázně, takes about two hours. Head southwest out of the city along the D5 motorway past Plzeň, turning north on Hwy 21 at Bor.
Several fast trains per day run from Prague (261Kč, three hours) with a change at Plzeň. Regular (slow) trains link Mariánské Lázně and Karlovy Vary (66Kč, 1¾ hours). Trolleybuses 5 and 7 (12Kč) run from the station to the spa area, or you can walk (30 minutes).