Tayrona's eastern part features most of the attractions and tourist facilities, and it's by far the park's most popular area. Its main gateway is El Zaíno, 34km east of Santa Marta on the coastal road to Riohacha.

Other entrances to the park include Palangana, from where it's possible to access Bahía Neguange by a rather rough road if you have your own transport. From Bahía Neguange there are launches to Playa Cristal, a gorgeous palm-fringed beach with several seafood restaurants where you can enjoy fresh fish and a cold beer after your swim. You can also catch a daily boat to Playa Cristal from Taganga.