Getting There & Away
With the introduction of new regulations, only boats operating out of Colombian ports may offer trips to Isla Malpelo. Basically that means boats operating out of Buenaventura. But be aware that many pack lots of divers onto each trip and most don't usually carry nitrox.
One well-run boat is the Sea Wolf operated by the Pacific Diving Company in Cali. Expect to pay around COP$7,000,000 per diver for three days of diving, and up to COP$9,200,000 for eight days in the water. Prices are slightly lower if you share a room.