Santiago's unique neighborhoods provide the backdrop for your stay. For easy access to museums and restaurants, consider the Centro, budget-friendly Barrio Brasil or nightlife districts like classy Barrio Lastarria and raucous Bellavista. For fancier digs and sophisticated dining – but limited access to most major sights – head to leafy Providencia, trendy Barrio Italia or well-heeled Las Condes.
For longer stays, consider renting a furnished apartment. Contact Chile is a reliable rental service, while Augustina Suites provides furnished mini-apartments that are well situated in the Centro.