This new route links the hard-to-reach southern end of the Carretera Austral directly with Puerto Natales, with stops in Puerto Eden. The 700km trip takes approximately 41 hours in the ferry Cruz Australis. The end point of Puerto Yungay has no services itself, it sits between Caleta Tortel and Villa O'Higgins, with transfers available from there.
It goes 10 times per month in high season, check the website for details. Buy tickets online or through a Puerto Natales travel agency.