If you want to dump the car in Puerto Montt, friendly José is one of the few that will let you (CH$6000). Rates start at CH$25,000 including insurance and whether you're broken down or lost, José has your back 24/7.…
Bus transportation to and from Santiago is best with TurBus (eight or so daily departures), with a ticket office in town and their own station east of the center (Blanco Encalada 2245).
Temuco is a major bus hub. Long-haul buses run from the Terminal Rodoviario, at the northern approach to town.
Villarrica has a main (mostly regional) bus terminal, though a few companies have separate offices nearby.
TurBus serves main cities located along the Panamericana and frequent services to Santiago.
Door-to-door shuttle service to Aeropuerto de La Araucanía. Reserve 24 hours in advance.
Cruz del Sur serves majpr points along the Panamericana as well as the island of Chiloé.
Igi Llaima/Nar-Bus runs buses to Melipeuco and Argentina out of their own station.
The hectic Terminal de Buses Rurales serves local and regional destinations.
Directly on the highway to Lonquimay.