Flights & getting there
All Santa Cruz–Concepción buses pass through San Xavier (B$30, six hours), stopping on the main road a short walk from the main plaza. Connections to Concepción pass through every three hours or so from midday to midnight. Along the way look out for the Piedras de Paquio rock formation on your right side at Km 322. Trufis (shared car or minibus) for San Ignacio de Velasco (via Concepción) leave at 12pm and 3pm.
For the return to Santa Cruz you can avoid the often overcrowded buses by taking a trufi (B$35, four hours); these leave when full. Listen for them honking for passengers along the main road. Otherwise, buses for Santa Cruz leave at 11:30am, 2:30pm, 5:30pm, 6:30pm, 7:30pm, 9pm and 11pm.
You can check transport times at the Tourist Office.