Rurre’s airport is 4km north of town. Amaszonas has daily flights to La Paz (B$480 and up) but at the time of research only one plane – you're out of luck if that's 'in maintenance.' TAM sporadically offers flights between La Paz and Rurre.
The brief flight to La Paz is an affordable way of avoiding the arduous bus journey. Flights sell out fast and are frequently cancelled during bad weather. You will be refunded only 75% of the ticket value if your flight is cancelled and you’re not prepared to wait around for the next one. Be sure to reconfirm your ticket the day before flying, otherwise you may find yourself without a seat.
If you wish to fly to Riberalta or Guayaramerín, you need to go to Trinidad.
The boat journey from Guanay to Rurre down Río Kaka and Río Beni is – for fans of slow travel – certainly the most scenic way to reach town from La Paz. Thanks to the Guayaramerín road, there’s little cargo transportation further down the Río Beni to Riberalta these days. You’ll need a dose of luck to find something and will have to negotiate a fair price for the boat (about B$4,000). The trip may take as long as three days.
The main bus terminal is across from the airport and a B$5 moto-taxi ride from town. All buses leave from here, though shared taxis to San Borja and Caranavi also depart when full from the old terminal by the cemetery. Prices do not vary between companies.
Several daily services make the daunting trip from Rurrenabaque to La Paz (B$70, 13 to 15 hours), via Yolosa (B$60, 12 hours), the hop-off point for Coroico. If you find the narrow, twisting Andean roads and sheer drops a harrowing experience on a bus, another option is to bus it as far as Caranavi (B$70, five to seven hours) and take a shared taxi from there, the rest of the trip being the most scary, or picturesque, depending on your point of view.
The route to Trinidad (B$130, 10 to 13 hours) via San Borja (taxi/bus B$80/50, three hours) and San Ignacio de Moxos (B$100, seven hours) was once one of the worst in the country, but is now paved for much of the way. Buses currently run year-round on this route, as well as to Riberalta (B$120, 13 to 14 hours) and Guayaramerín (B$130, 14 to 15 hours), but you need a healthy dose of stamina, insect repellent and food if you’re going to attempt trips in the wet season. Departure times are erratic for these long-distance destinations and change day to day, so it's best to check at the station in advance.